To enhance drug delivery to the central circulation during PALS, what should you do when administering drugs into a peripheral IV?

Administering drugs by bolus injection into a peripheral IV is the correct approach to enhance drug delivery to the central circulation during Pediatric Advanced Life Support (PALS). When a drug is given as a bolus, it is rapidly pushed through the IV line and reaches the systemic circulation more quickly. This is particularly important in emergency situations where a swift pharmacological response can be critical in treating life-threatening conditions.

In the context of PALS, rapid delivery of medications can improve outcomes, especially in cases of cardiac arrest or arrhythmias, where immediate drug action is often necessary. The bolus method ensures the medication doesn't linger too long in the peripheral circulation where absorption may be delayed, thus making it more effective for urgent treatment scenarios.

While infusing drugs gradually may seem safer, it can result in prolonged time before the drug effects are observed, which is not ideal during critical events. Mixing the drug with dextrose may provide some benefits for specific medications but does not inherently enhance the rate of delivery into the circulatory system. Lastly, administering drugs only after compressions cease could significantly delay treatment, as effective drug therapy is essential during ongoing resuscitation efforts. Therefore, bolus injection stands out as the best method to ensure timely and effective drug delivery